| Bigloo | Fast Scheme-to-C and Scheme-to-JVM compiler | R5 |
|---|---|---|
| Chez Scheme | Cross-module optimizing native-code compiler | R6 |
| Chibi-Scheme | Small embeddable interpreter with many optional libraries | R7 |
| CHICKEN | Scheme-to-C compiler with a big, friendly community | R5 R7 |
| Cyclone | New Scheme-to-C compiler with native threads | R7 |
| Gambit | Fast, concurrent, retargetable optimizing compiler | R5 R7 |
| Gauche | Fast script interpreter with many built-in libraries | R5 R7 |
| Gerbil | Scheme with actors and objects built on Gambit | R5 R7 |
| Guile | Main Scheme implementation of the GNU project | R6 R7 |
| JazzScheme | Object-oriented GUI and IDE built on Gambit | R5 |
| Kawa | JVM compiler with many extensions to Scheme | R7 |
| Loko | Bare-metal native-code compiler | R6 R7 |
| MIT/GNU Scheme | Native-code compiler and development environment | R5 R7 |
| Mosh | Fast and complete R6RS interpreter | R6 R7 |
| Racket | Native code compiler | R5 R6 R7 |
| s7 | Embeddable interpreter for music applications | R7 |
| Sagittarius | Script interpreter with many built-in libraries | R6 R7 |
| SCM | Portable C implementation that begat Guile and SLIB | R5 |
| STklos | Interpreter with CLOS object-oriented GUI | R7 |
| Ypsilon | Incremental native-code compiler with concurrent GC | R6 R7 |